HonorHealth Laboratories is implementing a new syphilis testing algorithm to improve efficiency while maintaining the same high diagnostic standards you expect. This network-wide change affects all providers and requires a new test order code.

What’s changing

Beginning Tuesday, Sept. 16, syphilis testing will transition from the traditional algorithm to the reverse algorithm. This CDC-approved approach uses automated treponemal screening as the initial test, followed by quantitative nontreponemal testing (RPR) for positive results.

Key benefits:

• More efficient testing workflow for our laboratory volume
• Automated screening reduces processing time
• Same diagnostic accuracy and clinical interpretation

Action required

New primary test order:

• Syphilis Scrn w/rflx RPR and Titer, or TPPA [LAB7244]
• Use for all patients except newborns

Neonatal testing (no change):

• RPR w/ Reflex to Titer/TPPA [LAB7008]
• Continue using current order for infants under one year of age

Note: Clinical interpretation and diagnostic accuracy remain unchanged.

Questions?

For questions about the new testing algorithm or technical issues, contact the HonorHealth Laboratory Network or view the SBAR.

This update aligns with CDC recommendations and reflects best practices for laboratory efficiency while maintaining optimal patient care.