Critical drug shortages
As you know, drug shortages can occur for many reasons, including manufacturing and quality problems, delays and discontinuations. Our goal is to keep you informed about any issues we are currently experiencing, as well as what steps are being taken to deal with these shortages.
Please see the chart below for details about current critical drug shortages, our mitigation strategy for these drugs and any additional notes about supply. For the latest updates and memos regarding drug shortages, please refer to HonorHub.
| CRITICAL DRUG SHORTAGES | ||
| Medication | Mitigation strategy | Notes |
| Amiodarone (NEXTERONE) IV premix | Sites to shift to compounding bags when needed | ~14 days on hand |
| Ciprofloxacin IV premix | Alternative active redirecting to IV levofloxacin or PO ciprofloxacin | – |
| Clindamycin phosphate 150 mg/mL injection | Removed from intra-operative irrigation builders | – |
| Etomidate injection | PAR level reduction and central inventory consolidation | > 14 day supply in Pyxis |
| Glucagon 1 mg SDV (diagnostic kits) | Use of emergency kits containing diluent in syringe | – |
| Ketamine injection | Concentration provided will vary based on site specific inventory | > 14 days on hand |
| Lidocaine injection | Use of alternative local anesthetics, varies based on use case | – |
| Mannitol 25% injection | Evaluating 20% premix bags as potential alternative but supply also weak | – |
| Oxytocin injection / 503B premixes | Sites compounding as needed and stocked up on larger vials to support | > 10 days on hand |
| Sodium bicarbonate 4.2% 5 mEq (10 mL) injection – infant | Use vials for kits as syringes are unavailable | – |
| Sodium bicarbonate 8.4% 10 mEq (10 mL) injection – pediatric | Use vials for kits as syringes are unavailable | – |
| Sodium bicarbonate 8.4% 50 mEq (50 mL) injection – adult | Use vials for kits as syringes are unavailable – securing new source for syringes | – |